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Endocrinology

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Question:

What is MEN 1?

Author: H K



Answer:

Auto dominant inactivation of MENIN gene on chromosome 11, high penetrance for PHPT which is usually initial presentation of the disease, 90-95% of pt w/MEN 1 develop PHPT often at younger age than usual, multiple gland disease in this case so we need subtotal/total parathyroidectomy w/autotransplantation, pt can also have pituitary lesions.


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H K
H K