Question:
Two major mechanisms are RESPONSIBLE FOR TOLERANCE:
Author: LEIGHTON DWIGHT OBILLOSAnswer:
1 due to a DECREASED AMOUNT OF TOXICANT REACHING THE SITE where the TOXIC EFFECT IS PRODUCED (dispositional tolerance) 2 due to a REDUCED RESPONSIVENESS of a TISSUE to the CHEMICAL
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Author
LEIGHTON DWIGHT OBILLOS