What is systemic CD?

Generalized dermatitis/ exanthema in flexural areas (Baboon syndrome) Can also develop in previous CD/ positive patch test sites w/systemic exposure to allergen (ingestion/infusion..) Pathophysio similar to ACD, initiated by T cells. Most common causes are metals (mercury/nickel/gold), medications (Abx, steroids, aminophyllin, estradiol topical), plants and herbal products (Balsam of Peru...)