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Hematology

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Question:

What are red cell disoders?

Author: H K



Answer:

Reduced number or Hb concentration (Anemia) body gets O2 deprived and SoB that is due to either decrease in production or increase in loss Decreased production (by nutritional deficiency (B12, iron, folate), reduced erythroid cells by malignancy, ineffective red cell formation in case of thalassemia and chronic disease/ kidney problem) Increase in red cells (polycythemia) causes problems like thick blood, increased risk of clot, may be natural response to hypoxia high EPO, but can occur due to clonal expansion of red cell precursors (polycythemia vera) EPO normal or low


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H K
H K