TOXICOLOGY: (ATTRIBUTES OF TARGET MOLECULES)

1 TO IDENTIFY A TARGET MOLECULE as being RESPONSIBLE FOR TOXICITY, it should be demonstrated that the ultimate toxicant: __

Question

(ATTRIBUTES OF TARGET MOLECULES)

1 TO IDENTIFY A TARGET MOLECULE as being RESPONSIBLE FOR TOXICITY, it should be demonstrated that the ultimate toxicant: __

LEIGHTON DWIGHT OBILLOS · Accepted Answer

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1 REACTS WITH THE TARGET and adversely affects its function

2 Reaches an EFFECTIVE CONCENTRATION at the target site,

3 ALTERS THE TARGET in a way that is mechanistically related to the observed toxicity.

(ATTRIBUTES OF TARGET MOLECULES) 1 TO IDENTIFY A TARGET MOLECULE as being RESPONSIBLE FOR TOXICITY, it should be demonstrated that the ultimate toxicant: __