TOXICOLOGY: EFFECTS OF TOXICANTS ON TARGET
MOLECULES
(Dysfunction of target molecules)

1 Many proteins contain critical moieties necessary for assembly of macromolecular complexes or catalytic activity.

These molecules UNDERGO COVALENT AND/OR OXIDATIVE ALTERATION by xenobiotics, result in __

2 Toxicants may obstruct DNA's ability to serve as a
template. The covalent binding of chemicals to DNA causes __ during replication

Question

EFFECTS OF TOXICANTS ON TARGET
MOLECULES
(Dysfunction of target molecules)

1 Many proteins contain critical moieties necessary for assembly of macromolecular complexes or catalytic activity.

These molecules UNDERGO COVALENT AND/OR OXIDATIVE ALTERATION by xenobiotics, result in __

2 Toxicants may obstruct DNA's ability to serve as a
template. The covalent binding of chemicals to DNA causes __ during replication

LEIGHTON DWIGHT OBILLOS · Accepted Answer

.

1  aberrant signal transduction and/or poor control of the cell's energy and metabolic homeostasis

2 Nucleotide mispairing

. 1 aberrant signal transduction and/or poor control of the cell's energy and metabolic homeostasis 2 Nucleotide mispairing