What is silicosis?

Fibrosing pneumoconiosis, in areas where particle deposits are most important and predominate at top of lungs centroacinary/ subpleural peribronchiolar territories forming nodules. Observed by lymph node and pleura draining, we see anthracosis linked to accumulation of carbon particles and soot. 3 pathologies (alveolar lipoproteinosis (acute w/massive exposure), TB, cancer) Silicotic nodules (very limited, maybe calcified, macrophages containing birefringents in polarized light (talc, mica and silicates) replaced by collagen gradually, old lesions are acellular, hyaline fibrosis w/swirling arrangment