Question:
How is morphoolgy of thrombus?
Author: H KAnswer:
Three parts: head (white thrombus made of platelet and fibrin adhering to the wall) Body (mixed thrombus made of RBC/WBC/platelets and fibrin, heterogenous and striated appearance (Zahn's striae), mechanism of alternation is explained by tubrbulence following head obstacle, so we see red bands, white bands) Tail (red thrombus, formed of coagulated blood w/a little fibrin, floating downstream of the vessel). They are focally attached to endothelia and spread to heart, develop retrograde direction from point of attachment (Arterial thrombi) while venous extend in direction of blood flow. spreading part of thrombus is poorly attached to endothelia and can become fragmented and migrated in blood as embolus.
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