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Anapath

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Question:

How is the mechanism of an infarct?

Author: H K



Answer:

Ischemia leads to anoxia lead to anaerobic glycolysis, no glycogen, oxidative phosphorylation stops, no ATP, K+ go out and Ca2+ become intracellular, phospholipase activity increase, membrane damage permits water entry to cells, then necrosis of epithelia by release of lysosomal enzymes, leading to cell death (apoptosis)


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H K
H K