Question:
How are drug interactions in non depolarizing blockers?
Author: H KAnswer:
Anticholinesterases (overcome action of nondepolarizing blockers, but with increased dosage they can cause depolarizing block as a result of elevated Ach concentrations at end-plate membrane) Aminoglycoside Abx (Gentamycin, inhibit Ach release competing with Ca ions, synergize with curare and other competitive blockers enhancing blockade) Ca Channel Blockers (increase block in curare)
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