Question:
What are the possible consequences of APS?
Author: H KAnswer:
Cardiovascular (CVA, sinus thrombosis, cardiac valvupathy, MI, DVT in vein, intracranial thrombos arterial, CAD) Dermatologic (livedo reticularis [poor prognosis irresponsive to tx], purpura, infarct/ulcer) Hemato (thrombocytopenia, hemolyic anemia, thromboembolism) Musculoskeletal (avascular necrosis of bone /infarction/ hemorrhage) Neuro (stroke, ischemic attack, cognitive dysfunction, migraine R/O MS) OBGYN (spontaneous abortion, preterm delivery, preeclampsia, placental insufficiency) Ophthalmo (ocular thrombosis) Pulmo (embolism, pulmo HTN) Kidney (R/O SLE (IC) vs APS (thrombosis), liver and GI (liver T) CAPS (accelerated APS multiorgan failure over short time typically days to weeks, very poor prognosis)
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