How is epidemiology of OA?

 United States and international statistics  On the basis of the radiographic criteria for osteoarthritis, more 50% of adults older than 65 years are affected by the disease  the most common articular disease  Age-related demographics  Symptoms typically do not become noticeable until after the age of 50 years  The prevalence of the disease increases dramatically among persons older than 50 years, likely because of age-related alterations in collagen and proteoglycans that decrease the tensile strength of the joint cartilage and because of a diminished nutrient supply to the cartilage.  Sex-related demographics  Women>men specially DIPs, knees, erosive OA  Race-related demographics