What is giant cell arteritis?

• This vasculi7s occurs in older individuals and affects women more oSen than men. • Primarily large and medium size arteries are affected. • The pathology is that of focal granulomatous lesions involving the en7re arterial wall; it may be associated with polymyalgia rheuma7ca • Obstruc7on of medium-size arteries (e.g.， temporal and ophthalmic arteries) and major branches of the aorta and the development of aor77s and aor7c regurgita7on are important complica7ons of the disease. • High -dose glucocor7coid therapy may be effec7ve when given early.