What are neoplasia of thyroid?

Mostly Solitary palpable nodule, 4:1 (F:M), incidence increases with age, mostly benign in nature (10:1), thyroid cancers are mostly indolent (inactive), and usually solitray nodules are more neoplastic than multiple ones. Red Flags (young pt, Men, Hx of irradiation Multiple genetic pathways in thyroid carcinogenesis (PAX8/PPRAG unique for thyroid cancer/RET oncogene)