Question:
How is dx of cold agglutinins AIHA?
Author: H KAnswer:
• Evidence of hemolysis (eg, high reticulocyte count, high LDH, high indirect bilirubin, low haptoglobin) • Positive direct antiglobulin (Coombs) test for C3d • Cold agglutinin titer of ≥64 at 4°C • Blood smear, RBC agglutination
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Author
H K