What is presentation of paroxysmal cold hemoglobinuria?

• Signs and symptoms related to intravascular hemolysis (back or abdominal pain, weakness, nausea or vomiting, fever or chills, and/or dark or red urine), typically are self-limited and correlate with cold exposure. • Positive direct Coombs test for complement. Initial testing will show anemia, low haptoglobin, high (LDH) and bilirubin, and free hemoglobin in serum and urine. • Patients with these findings can be tested for the Donath-Landsteiner antibody