What are some prerequisits in blood transfusion?

Red Blood Cells (RBCs): Anucleated cells. Each hemoglobin (Hb) molecule comprises four heme groups, consisting of two alpha and two beta subunits. Conditions resulting from the loss of a heme group include thalassemia (minor vs. major). Adult Bone Marrow: Located in the femur, sternum, and hip. Bone marrow aspiration is typically performed two finger-widths below the sternal notch or in the hip, yielding a fluid containing RBCs, white blood cells (WBCs), and platelets. RBC Renewal: RBCs are replenished approximately every 120 days. Continuous RBC production without disruption leads to constitutive polycythemia or erythrocytosis. HbA1c Testing: Conducted every three months, this test measures glucose levels attached to Hb, reflecting RBC turnover.