Question:
What is primary hemostasis?
Author: H KAnswer:
Platelet Adhesion: Injury to blood vessels exposes subendothelial collagen, triggering platelet adhesion. Von Willebrand factor (vWF) plays a crucial role in mediating the adhesion of platelets to exposed collagen. Platelet Activation: Adhered platelets become activated, leading to changes in their shape and release of granule contents, including adenosine diphosphate (ADP) and thromboxane A2 (TXA2). Platelet Aggregation: Activated platelets recruit additional platelets to the site of injury through the binding of fibrinogen to glycoprotein IIb/IIIa receptors, resulting in platelet aggregation and formation of a platelet plug
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