Question:
How is stem cell infusion?
Author: H KAnswer:
Infusion - 20 minutes to an hour, varies depending on the volume infused. The stem cells may be processed before infusion, if indicated. Depletion of T cells can be performed to decrease GVHD. Premedication with acetaminophen and diphenhydramine to prevent reaction. Infused through a CVL, much like a blood transfusion. Anaphylaxis, volume overload, and a (rare) transient GVHD are the major potential complications involved. Stem cell products that have been cryopreserved contain dimethyl sulfoxide (DMSO) as a preservative and potentially can cause renal failure, in addition to the unpleasant smell and taste.
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