How is dependence and withdrawal of amphetamines?

Dependence and withdrawal: The risk of methamphetamine dependence with regular use is high. Dependence results in deficits in memory and decision-making and verbal reasoning, which can continue months after abstinence. Acute withdrawal (7-10 days): typically begin and peak shortly after someone’s last use (which means within 24 hours after their last use): Features: - severe, profound unhappiness which can lead to suicidal thoughts - irritability; anxiety - extreme sleepiness and fatigue - intense cravings - paranoia Longer term withdrawal (up to months): inability to feel pleasure; profound unhappiness; impaired social functioning; intense craving; anxiety; mood swings; irritability; and disrupted sleep patterns