Question:
What are sites of action of diuretics?
Author: H KAnswer:
5 main classes: Loop (act on ascending Henle's Loop) Thiazide (act on distal convoluted tubule) Carbonic-Anhydrase Inhibitors (on proximal convoluted tubule) Potassium-Sparring Diuretics (Cortical collecting tubule aldosterone sensitive principal cells [aldosterone antagonists and Na+ channel blockers]) Osmotic Diuretics (proximal convoluted tubules and descending henle's loop)
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