How are pharmacokinetics of beta blockers?

Fat soluble/Water soluble Fat soluble (absorbed 80%, high protein binding and passage through membrane, high hepatic metabolism, elimination in bile [Labetalol, Metoprolol, Propanolol]) Water soluble (incomplete intestinal absorption, low passage, very low hepatic metabolism, renal elimination [atenolol, nadolol, sotalol]) Imp to know ISA in acebutolol, pindolol and not propanolol.