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Pharmacology

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Question:

What is Topiramate?

Author: H K



Answer:

Block voltage gated Na+, enhance action of GABA Rs, reduce high-voltage Ca2+ currents L type. Uses: partial and generalized tonic-clonic seizures, migraine prophylaxis Minimal plasma protein binding, rapidly absorbed, moderate metabolism. Effects: OCPs less effective (like phenytoin) acute myopia.


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Author

H K
H K