How is tx of UUI?

The first-line treatment includes teaching the patient some behavioral therapies such as bladder training and toileting habits, lifestyle modifications, voiding diary, dietary changes, and avoiding bladder irritants (such as caffeine, smoking), pelvic floor muscle training (PFMT), and biofeedback Some antimuscarinic agents currently available for the treatment of urge incontinence include oxybutynin, tolterodine, fesoterodine, trospium, darifenacin, and solifenacin. The beta-3 adrenoreceptor agonists cause direct relaxation of detrusor muscles