How is immunological pathogenesis of cutaneous drug reactionss?

• Type I: IgE dependent: urticaria, angioedema, anaphylaxis. Ex: insulin • Type II: cytotoxic reactions: hemolysis, purpura. Ex: peni, cerebral, sulfa drugs, rifampicin • Type III: IC: Vasculitis, serum sickness, urticaria Ex: quinine, chlorpromazine, salicylates, sulfonamides • Type IV: Delayed HS: eczema, rash, photoallergy. Ex: topical (neomycin, ketoprofen)