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Question:

How is microscopy of microscopic angiitis?

Author: H K



Answer:

• Segmental fibrinoid necrosis of the media and focal transmural necrotizing lesions; granulomatous inflammation is absent. • These lesions morphologically resemble PAN but typically spare medium-sized and larger arteries; consequently, infarcts are uncommon. • In some areas (typically postcapillary venules), only infiltrating neutrophils, many undergoing apoptosis, are seen, giving rise to the term leukocytoclastic vasculitis


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H K
H K