What are splenic lymphomas?

• Wide and heterogeneous array of diseases. • Clinical behavior spans from indolent to highly aggressive. • Spleen rarely represents the exclusive site of the lymphomatous burden. • Distinguish pathologic conditions primarily involving the spleen v/s those in which splenomegaly presents as an epiphenomenon of hepatic or systemic diseases. • Diagnostic workup: PB, BM, Splenectomy PB evaluation • PB examination is therefore a mandatory step in the diagnostic workup of SLs. • Almost invariably show the presence of neoplastic cells in the PB +/- Flow for peculiar cell types