How is macroscopy of neuroblastoma?

Range in size from minute nodules (the in situ lesions) to large masses weighing more than 1 kg. In situ neuroblastomas are reported to be 40 times more frequent than overt tumors. The great preponderance of these silent lesions spontaneously regress, leaving only a focus of fibrosis or calcification in the adult. Some neuroblastomas are sharply demarcated with a fibrous pseudocapsule, but others are far more infiltrative and invade surrounding structures, including the kidneys, renal vein, and vena cava, and envelop the aorta On transection, they are composed of soft, gray-tan, brainlike tissue. Larger tumors have areas of necrosis, cystic softening, and hemorrhage. Multifocal in 10% des cas