How is invasion of neuroblastoma?

Locally aggressive tumor invading the kidney Most common metastasis are to the liver, bones, ovaries, lymph nodes, testes and paratesticular area Bone metatstasis are multiple, sometimes symmetrical (differential Dg with Ewing) The osteomedullar biospy enters the routine work upof a NB Age, stage, and NMYC amplification are the most important prognostic features; children younger than 18 months usually have a better prognosis than older children, while children with higher-stage tumors or NMYC amplification fare worse.