What is proliferative disease w/out atypia?

➢ associated with a slightly increased risk of breast cancer. ➢ includes epithelial hyperplasia, sclerosing adenosis, complex sclerosing lesion, and papilloma. ➢ Each is associated with varying degrees of epithelial cell proliferation ➢ in epithelial hyperplasia, increased numbers of both spindled myoepithelial cells and epithelioid luminal cells expand ductal and lobular spaces