What are clinical features of melanoma?

➢ Melanoma of the skin usually is asymptomatic, although pruritus may be an early manifestation. ➢ The most important clinical sign is a change in the color or size of a pigmented lesion. ➢ The main clinical warning signs are as follows: 1. Rapid enlargement of a preexisting nevus 2. Itching or pain in a lesion 3. Development of a new pigmented lesion during adult life 4. Irregularity of the borders of a pigmented lesion 5. Variegation of color within a pigmented lesion ➢ These principles are expressed in the so-called “ABCs” of melanoma: asymmetry, border, color, diameter, and evolution