How is endometrial carcinoma?

➢ It generally appears between the ages of 55 and 65 years and is uncommon before age 40. ➢ Endometrial carcinoma can be broadly divided into two histologically and pathogenically distinct categories: endometrioid and serous carcinoma. ➢ There are other less common types of endometrial carcinoma, such as clear cell carcinoma and mixed Mullerian tumor (carcinosarcoma) ➢ Closely resemble normal endometrium and may be exophytic or infiltrative ➢ They include a range of histologic types, including those showing mucinous, tubal (ciliated), and squamous differentiation. ➢ Endometrioid carcinomas often infiltrate the myometrium and can enter vascular spaces (lymphovascular invasion). ➢ They may also metastasize to regional lymph nodes ➢ Endometrioid carcinomas are graded 1 to 3, based on the degree of differentiation.