How is leiomyoma presentation?

➢ Typically sharply circumscribed, firm graywhite masses with a characteristic whorled cut surface. ➢ They may occur singly, but more often occur as multiple tumors that are scattered within the uterus, ranging from small nodules to large tumors that may dwarf the uterus. ➢ Some are embedded within the myometrium (intramural), whereas others may lie immediately beneath the endometrium (submucosal) or the serosa (subserosal). ➢ On histologic examination, the tumors are characterized by bundles of smooth muscle cells mimicking the appearance of normal myometrium. ➢ Foci of fibrosis, calcification, and degenerative softening may be present.