What is use of MIBI?

-Nuclear medicine scanning with radiolabeled sestamibi MIBI = accumulate in parathyroid adenomas -This radionuclide is concentrated in thyroid and parathyroid tissue but usually washes out of normal thyroid tissue in under an hour -It persists in abnormal parathyroid tissue -On delayed images, an abnormal parathyroid is seen as a persistent focus of activity -The scan's sensitivity for solitary adenomas = 60-90% -The main weakness of this test is in diagnosing multiglandular disease (sensitivity 50%)