What is glioblastoma?

➢Gliomas account for more than 80% of all primary brain tumors in adults. ➢Most are located above the tentorium and within the cerebral hemispheres. ➢ GB are poorly circumscribed, large masses and have extensive necrosis ➢ Patients may initially have a new-onset seizure disorder, headaches, or focal neurologic deficits. ➢Although this neoplasm is highly aggressive within the brain, metastases outside the CNS are rare. ➢ IDH Wildtype!!!