How is medulloblatoma morphology?

➢Poorly differentiated round blue cells with scant cytoplasm and hyperchromatic nuclei are shown. ➢On occasion the cells form pseudorosettes called Homer Wright rosettes with cells surrounding eosinophilic circular zones. ➢The nodular desmoplastic variant has areas of stromal response with “pale islands” that have more neuropil and show greater expression of neuronal markers. ➢The large cell variant has large irregular vesicular nuclei, prominent nucleoli, and frequent mitoses