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Clinical Immunology

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Question:

How is skin and mucosal allergies?

Author: H K



Answer:

Urticaria is characterised by weals (hives) ==> pale central area surrounded by redness and swelling or angioedema (swellings in 10%) or both in 40% Weals (wheals) or hives are generally raised, circumscribed, erythematous papules and plaques (that blanch with pressure), involving the dermis and epidermis, and classically have a central area of pallor, often round in shape and of variable size, Outbreaks that may occur anywhere on the skin are usually very itchy (it may have a burning sensation) and transient; It lasts from a few minutes to 24 hours. Urticaria/angioedema: According to level of mast cell degranulation clinical signs are superficial (Urticaria) or deep swelling (Angioedema)


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H K
H K