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Clinical Immunology

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Question:

Why does DTH evolve?

Author: H K



Answer:

➢ DTH evolved as a protective host mechanism to combat various intracellular pathogens, including mycobacteria, virus, fungi, and certain parasites; however, excessive DTH responses can lead to immunopathology, exhibited by granuloma formation, fibrosis or even tissue necrosis. ➢ DTH reactions are prominent in autoimmune diseases, tumor immunity and transplant rejection


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H K
H K