Question:
Why does DTH evolve?
Author: H KAnswer:
➢ DTH evolved as a protective host mechanism to combat various intracellular pathogens, including mycobacteria, virus, fungi, and certain parasites; however, excessive DTH responses can lead to immunopathology, exhibited by granuloma formation, fibrosis or even tissue necrosis. ➢ DTH reactions are prominent in autoimmune diseases, tumor immunity and transplant rejection
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