Question:
What are bacterial vaccines based on purified toxoids?
Author: H KAnswer:
Exotoxins of Clostridium tetani and Corynebacterium diphtheriae are responsible of their pathogenicity Toxoids are modified non pathogenic exotoxins Neutralizing anti-toxoid antibodies are efficient in preventing intoxication Toxins enter cells via cellular receptors, then dissociate releasing active chain which poison cells, protected by Ab blocking the toxin.
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H K