Question:
What are applications of usage of recombinant cytokines in immunotherapy of chronic infections/
Author: H KAnswer:
Chronic hepatitis B and hepatitis C IFN-a (Roferon): Inhibits viral propagation in healthy cells Pegylated IFN-a (Rebetol) less degradable (adults only) Approved by the FDA HIV: IFN-a for the treatment of Kaposi sarcoma (approved by the FDA) IFN-g prevents mother-fetus transmission of HIV IL-2 combined to 2 anti-retroviral drugs increases the number of CD4 cells Herpes simplex: IFN a
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