What are various monoclonal Abs in cancer therapy?

Origin: — Chimeric — Humanized — Human Structure: — Complete Ig molecules: maintain the effector function — Fab or Fab’2 : smaller, better tumor penetration — scFv: single chain variable fragment (fusion of VH-VL) Chemical composition: — Purified naked antibody (alone) — Conjugated antibody: radioactive, immunotoxin, ADEPT