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FVMB Licence 2020

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Question:

The reaction below is catalyzed by an enzyme that has as coenzyme pyridoxal phosphate, a derivative of vitamin B6: A + B↔C + D The correct statement about this reaction is:

Author: Exciteful Elk



Answer:

All the above statements are correct if A is glutamic acid and B is pyruvic acid, then C is α-ketoglutaric acid and D is alanine; if A is glutamic acid and B is oxalylacetic acid, then C is α-ketoglutaric acid and D is aspartic acid; if the answer "a" is correct, then the enzyme is called glutamate-pyruvate transaminase (GPT) or alanine aminotransferase (ALT); if the answer "b" is correct, then the enzyme is called glutamate-oxalylacetate transaminase (GOT) or aspartate aminotransferase (AST)


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Alternative answers:

If A is glutamic acid and B is pyruvic acid, then C is α-ketoglutaric acid and D is alanine
If A is glutamic acid and B is oxalylacetic acid, then C is α-ketoglutaric acid and D is aspartic acid
If the answer "a" is correct, then the enzyme is called glutamate-pyruvate transaminase (GPT) or alanine aminotransferase (ALT)
If the answer "b" is correct, then the enzyme is called glutamate-oxalylacetate transaminase (GOT) or aspartate aminotransferase (AST)