E. Gabapentin

Gabapentin is an analog of GABA. However, it does not act at GABA receptors, and it neither enhances GABA actions nor is converted to GABA. Its precise mechanism of action is not known. It is approved as adjunct therapy for partial seizures and for treatment of postherpetic neuralgia.Gabapentin has been shown to be well tolerated by the elderly population with partial seizures due to its relatively mild adverse effects. It may also be a good choice for the older patient because there are limited or no reported associated pharmacokinetic drug interactions.