VII. TOXICOLOGY OF ACETYLCHOLINESTERASE INHIBITORS

AChE inhibitors are commonly used as agricultural insecticides in the United States, which has led to numerous cases of accidental intoxication with these agents. In addition, they are frequently used for suicidal and homicidal purposes. Toxicity with these agents is manifested as nicotinic and muscarinic signs and symptoms. Depending on the agent, the effects can be peripheral or affect the whole body.