Child With a Physical and Mental Disorder (CH 32)
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List some environmental factors contributing to congenital heart defects | Intrauterine rubella exposure Maternal alcoholism Diabetes Advanced maternal age Maternal drug ingestion |
List some genetic factors contributing to the development of congenital heart defects: | Sibling or parent with CHD Chromosomal anomalies Other noncardiac congenital anomalies |
Oxygenated blood enters the fetal heart via the: | Inferior vena cava |
The four CHD categories are related to: | Increased pulmonary blood flow Decreased pulmonary blood flow Obstruction to systemic blood flow Mixed blood flow |
Administration of ________ is effective in closing the ductus arteriosus in full-term and premature newborns | Indomethacin |
Which palliative procedure can be performed in infants with symptomatic VSD's? | Pulmonary artery banding |
What is the most common CHD resulting in decreased pulmonary blood flow? | Tetralogy of Fallot |
Tetralogy of Fallot involves four defects: | 1. Pulmonary stenosis 2. VSD 3. Right ventricular hypertrophy 4. Overriding aorta |
In coarctation of the aorta, blood pressure in the arm is _____ higher than that in the legs | 20 mm Hg |
Iron-deficiency anemia peaks in children between which ages? | 6 and 24 months |
List 3 iron-rich foods: | Red meat Legumes Iron-fortified cereals |
How is anemia defined? | A decrease in red blood cells, hemoglobin, or both |
What are the two classifications of anemia? | Hypoproliferative (defective production of erythrocytes) Hemolytic (premature destruction of erythrocytes) |
What are signs of mild to moderate anemia? | Irritability Weakness Decreased play activity Fatigue |
Hemoglobin values of 6 to 10 g/dL is considered: | Mild to moderate anemia |
What are the clinical signs of a hemoglobin below 5 g/dL? | Anorexia Skin pallor Pale mucous membranes Glossitis Spoon fingernails Inability to concentrate Tachycardia Systolic murmurs |
Why are adolescents at risk for iron-deficiency anemia? | Rapid growth rate Poor eating habits |
Health care provider usually prescribe ________ until the hemoglobin value returns to normal | Oral iron supplementation (ferrous sulfate) |
What should be taken with iron supplements? | Citrus fruits or juices |
Packed RBC's are given only to which children? | Severely anemic |
What will the stool look like while receiving iron therapy? | Dark, tarry, green |
What are some precipitating factors causing the sickling of erythrocytes? | Infection Fever Hypoxemia Dehydration High altitudes Cold Emotional stress |
Name the three types of sickle cell crisis: | 1. Vasoocclusive 2. Sequestration 3. Aplastic |
What happens to the red bone marrow in aplastic anemia? | Becomes yellow and fatty |
What is used to determine whether a patient has sickle cell trait or sickle cell disease? | Hemoglobin electrophoresis |
What is the only potential cure for sickle cell disease? | Bone marrow or stem cell transplantation |
Which gender is the carrier of hemophilia? | Transmitted by female carriers |
How many male births are affected by hemophilia? | 1 in 5000 male births |
In hemophilia, where does bleeding most frequently occur? | Within the joints and muscles |
What is the purpose of the infusion of the hormone desmopressin? | Prevent bleeding from occurring |
What does RICE stand for? | Rest Ice Compression Elevation |
The onset of ITP is seen in children of which ages? | 2 to 10 years |
What is the most serious complication of ITP? | Intracranial hemorrhage |
What are usually the first signs of ITP? | Ecchymosis and petechial rash (usually over bony prominences) |
A splenectomy eliminates the site of ________ ________ production | Platelet antibody |
What is the leading cause of disease in children past infancy? | Neoplastic disease (cancer) |
What is the most common form of leukemia in children? | Acute lymphoid leukemia (ALL) |
In leukemia, there is an overproduction of _______ which accumulate in the marrow. | Blast cells (immature WBC's) |
Which three problems develop as a result of the overproduction and accumulation of immature WBC's? | 1. Decrease in RBC production 2. Neutropenia leads to infection 3. Decrease in platelets, causing bleeding |
What is often the first symptom of leukemia? | Anemia with pallor and fatigue |
What is the route of choice for CNS prophylaxis? | Intrathecally (directly into cerebrospinal fluid) |
What is the drug of choice for CNS prophylaxis? | Methotrexate |
Which ages are considered to be high-risk when diagnosed with acute lymphoid leukemia (ALL)? | Younger than 1 and older than 10 |
What is the main diagnostic feature of Hodgkin's lymphoma? | Reed-Sternberg cells |
What is the common indicator in all immunodeficiency disorders? | Unusual or recurrent, severe infections |
Why does HIV target T helper lymphocytes? | They have more CD4+ receptors on their surface than any other cell |
What is the greatest threat to an HIV infected infant younger than one year? | Pneumocystis jiroveci pneumonia |
Juvenile idiopathic arthritis is more common in which gender? | Affects GIRLS twice as much as boys |
How is JIA characterized? | Chronic inflammation of the synovium with joint effusion |
What is the disadvantage of using DMARD's? | Increased chance of infection |
What do TNF blockers do? | Reduce pain, morning stiffness, and joint swelling |
What are the disadvantages of TNF blockers? | Increased risk of infection Increased chance of lymphoma or other cancer |
What are two examples of TNF blockers? | Etanercept (Enbrel) adalimumab (Humira) |
What is respiratory distress caused by? | A deficiency of surfactant |
What kind of feedings are contraindicated in an infant with RDS? | Nipple and gavage |
How is exogenous pulmonary surfactant administered? | Endotracheal tube directly into the lungs |
How should the infant with RDS be positioned? | On the side with head in alignment |
Frequent suctioning increases the risk for: | Bronchospasm Infection Pneumothorax Hypoxia Increased intracranial pressure |
What is the most effective preventative measure for RDS? | Prevention of premature delivery |
Infants who survive Bronchopulmonaary dysplasia are at risk for: | Chronic lung disease |
Bacterial pneumonias are most common in _____ and ______. | Infants and children |
What is the most common viral pneumonia in infants and children? | Respiratory syncytial virus (RSV) |
What kind of pneumonias typically run a longer course? | Staphylococcal |
How many infants die of SIDS? | 2 out of every 1000 |
SIDS is often associated with which factors? | Premature birth Low birth weight Multiple births CNS and respiratory dysfunctions |
What does postmortem examination reveal in an infant with SIDS? | Pulmonary edema and intrathoracic hemorrhages |