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Physiology

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Question:

State the effects of local anesthetics (LA) on the amplitude and duration of the action potential

Author: Donata Nshimyicizanye



Answer:

Local anaesthetics cross the lipid bilayer in an uncharged form and bind to the intracellular part of the Na V channels in the inactivated state LA creates an absence of pain sensation in a specific location of the body


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