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BBS2001 Threats and Defence Mechanisms
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Question:
What drugs/structures can be used to treat venous thrombosis?
Author: Mirte SchattorieAnswer:
Heparin: increases the activity of antithrombin, increasing the inhibition of factor Xa and thrombin vitamin K antagonists (warfarin): inhibition of vitamin K unables it to modify a lot of coagulation factors, less clotting as a result fibrinolysis (recombinant tPA): tPA will turn plasminogen into plasmin and plasmin will digest the clots. dabigatran, lepirudin, desirudin: direct inhibitors of either thrombin or factor Xa, no fibrin mesh formed.
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