Aortic Regurgitation: CHRONIC Etiology

(a) Cusp pathology: - Congenital diseases - unicuspid/ bicuspid/ quadricuspid aortic valve, AV prolapse, - Inflammatory - IE, rheumatic fever/disease - Degenerative - atherosclerosis, calcinosis (b) Abnormalities of aortic root & ascending aorta geometry: - Idiopathic anuloaortoectasy, Inflammatory CT diseases (Spondyloarthritis, ulcerative colitis), Arterial HTN, Aneurysm of sinus vasalva, Marfan's syndrome & Ehler's Danlos - syphilis aortitis, degenerative aneurysm of ascending aorta, bicuspid AV w/ aorthopathy