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LF205 L10-14

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Question:

Insulin/IGF-1 signalling and ageing in mammals!

Author: Alex Rapai



Answer:

Worms, flies: One insulin/IGF-1 receptor. Mammals: insulin receptor, IGF-1 receptor, insulin-receptor-like receptor. Insulin receptor: Mild reduction of function of IR gene: type 2 (non-insulin dependent) diabetes


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