Quinine Sulphate: -Indication -Patient counselling -Side effects -Prescribing -Interactions -Overdose

-Not routine treatment for nocturnal leg cramps- only give if necessary (weigh out risk/benefit) - If there is no benefit after at least 4 weeks- stop using it – DO NOT exceed the recommended dose -Tinnitus, impaired hearing, headache, nausea, disturbed vision, confusion, flushing, and abdominal pain – (rare) Thrombocytopenia- thought to be a hypersensitivity reaction Need to report any signs of thrombocytopenia: unexplained petechiae rash (pinpoint, round spots), bruising, or bleeding. -It should not be prescribed to those who have had previous side effects with quinine in drinks -It should not be prescribed to those who have had previous side effects with quinine in drinks -Significant interactions with digoxin and warfarin -Significant toxicity in overdose- can result in death or permanent visual loss